Research and Publications

Our research program is in the area of ophthalmic oncology looking at molecular biology of uveal melanomas and its impact on therapy.  We have a number of clinical studies on orbital lymphoid tumors, conjunctival melanomas, and manuscripts that have been and continue to be produced in those areas. Dr. Char is the author of three definitive textbooks in his field.  The following is a list of those books as well as a selection of recent publications based on research. 

  • Tumors of the Eye and Ocular Adnexa. Hamilton: BC Decker, Inc.  (in conjunction with the American Cancer Society 2001)
  • Clinical Ocular Oncology. Second edition. Philadelphia: Lippincott-Raven, 1998
  • Thyroid Eye Disease. Third edition. Boston: Utterworth-Heinemann, 1997
  • Char DH. Uveal Malignant Melanoma: Differential Diagnosis. In: Singh D, ed. Essentials of Opthalmic Oncology. Thorofare, NJ: SLACK Incorporated; 200:85-88
  • Onken MD, Worley LA, Char DH, Augsburger JJ, Correa ZM, Nudleman E, Aaberg Jr. TM, Altaweel MM, Bardenstein DS, Finger PT, Gallie BL, Harocopos GJ, Hovland PG, McGowan HD, Milman T, Mruthyunjaya P, Simpson ER, Smith ME, Wilson DJ, Wirostko WJ, Harbour JW. Collaborative Ocular Oncology Group Report Number 1: Prospective Validation of a Multi-Gene Prognostic Assay in Uveal Melanoma. Ophthalmology. 2012;119:1596-1603
  • Correa ZM, Harbour JW, Augsburger J, Char DH, Damato B, Finger PT. Role of Biopsy in the Management of Intraocular Tumors. Retina Times, issue 31, pp 27-32, 2009
  • Chappell MC, Char DH, Cole TB, Harbour JW, Mishra K, Weinberg VK, Phillips TL. Uveal Melanom: Molecular Pattern, Clinical Features, and Radiation Response. Am J Ophthalmology 2012; 154 (2)227-232.e2
  • Jusufbegovic D, Char D. Clinical variability of ocular involvement in mycosis fungoides. JAMA Ophthalmology. 2015;133:341-343
  • Walter SD, Chao DL, Feuer W, Schiffman J, Char DH, Harbour J. Prognostic Implications of Tumor Diameter in Association With Gene Expression Profile for Uveal Melanoma. JAMA Ophthalmol. 2016;134(7):734-740. doi:10.1001/jamaophthalmol.2016.0913
  • Char DH, Jaffee IM. Myomelanocytic choroidal tumor: cytopathologic diagnosis. 2017. Retina 37(2):1.
  • Polishchuk AL, Mishra KK, Weinberg V, Char DH. Temporal Evolution and Dose-Volume Histogram Predictors of Visual Acuity After Proton Beam Radiation Therapy of Uveal Melanoma. Int J Radiat Oncol Biol Phys. 2017 Jan 1;97(1):91-97.
  • Mishra KK, Afshar A, Thariat J, Char DH, et al. Practice considerations for proton beam radiotherapy of uveal melanoma during the COVID-19 pandemic: PTCOG Ocular experience [published online ahead of print, 2020 Apr 23]. Adv Radiat Oncol. 2020;10.1016/j.adro.2020.04.010. doi:10.1016/j.adro.2020.04.010